Dr. Mashour has published a new book entitled “Oxford Textbook of Neuroscience and Anaesthesiology” with Kristin Engelhard.
2017- CCS faculty receive new NIH funding to study the role of the hypothalamus in level of consciousness
Dr. Giancarlo Vanini will work with his co-PI, George Mashour, and other faculty in the Center for Consciousness Science to understand how sleep-promoting regions in the hypothalamus regulate the entry into and exit from the anesthetized state. Using cutting-edge chemogenetic techniques, they will also explore how these subcortical nuclei alter cortical connectivity and dynamics.
2016- CCS faculty receive NIH grant to study cortical connectivity in computational models, non-human primates, and surgical patients
CCS Directors Mashour and Lee have just been awarded a NIH R01 to conduct computational, neurobiological, and clinical studies of consciousness and anesthesia. CCS faculty Cindy Chestek (biomedical engineering) and Parag Patil (neurosurgery) are co-investigators.
2015- CCS receives grants from the National Institutes of Health and the James S. McDonnell Foundation to study brain networks as consciousness is lost and reconstituted
Dr. George Mashour and the CCS have been awarded major grants from the NIH and the prestigious James S. McDonnell Foundation to study consciousness in humans and nonhuman primates. The new NIH R01 will fund studies of healthy volunteers receiving ketamine and nitrous oxide; parallel studies examining cortical information transfer in the monkey brain during anesthetic state transitions will also be conducted. The McDonnell Foundation grant funds a translational neuroscience project conducted across multiple U.S. and Australian centers, led by the Center for Consciousness Science at the University of Michigan. The goal of this project is to study how the brain reconstitutes consciousness and cognition after major perturbations such as general anesthesia or seizures. The multidisciplinary teams assembled for the studies span the fields of neuroscience, physics, computational science, biomedical engineering, pain neurobiology, anesthesiology, neurosurgery, and psychiatry.
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Brito, M et al, "State-Dependent and Bandwidth-Specific Effects of Ketamine and Propofol on Electroencephalographic Complexity in Rats". Front Syst Neurosci 2020